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Crone's curse

Source Ultimate Wilderness pg. 144
Price 600 gp; Weight
Type inhaled; Save Fortitude DC 16
Onset 1d4 hours; Frequency 1/day for 6 days
Effect 1 Dex and Wis damage. As long as a creature has any ability damage from crone’s curse, the creature takes a –4 penalty on saving throws to resist the effects of extreme temperatures. Additionally, the creature gains vulnerability to cold and fire damage during this time, taking half again as much (+50%) damage from these forms of damage.
Cure 2 consecutive saves

Description

A blackish pollen produced by the night witch (a pale, vine-growing flower that blooms in the light of the moon and is hearty enough to survive very rugged and difficult environments), crone’s curse disorients those who inhale it and interferes with the body’s ability to regulate temperature. Merely walking through a field of night witch flowers is often sufficient enough to kick up a cloud of the nearly invisible black particles, which are a mere nuisance in temperate climates but can prove fatal to those exposed to them in deserts and tundra.